Stanford, California 94066

  • Coronary Artery Disease


This is a multi-center, randomized quality improvement project. At least 200 statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental coronary artery calcium (CAC) on a prior non-gated chest CT will be enrolled across the Stanford Healthcare System and the Palo Alto Veteran's Affairs Healthcare System. Patients will be randomized in a 1:1 fashion to notification or usual care arms. The primary aim of this project is to estimate the increase in 6-month statin prescription among statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental CAC on a non-gated chest CT who are randomized to receive notification of their findings vs. usual care.


Inclusion Criteria: - Non-gated chest CT between 2014-2019 - The presence of CAC confirmed by manual review by an experienced radiologist - Stanford affiliated primary care provider or endocrinologist for Stanford healthcare system patients and VA primary care provider for VA patients with at least 1 encounter since 2018 Exclusion Criteria: - Current or prior statin or PCSK9 inhibitor therapy - Prior diagnosis of ASCVD (coronary artery disease, peripheral arterial disease, cerebrovascular disease, coronary/peripheral revascularization) - Prior coronary imaging (cardiac CT, invasive coronary angiography) - Dementia - Metastatic cancer or active cancer undergoing chemotherapy - History of medical nonadherence



Primary Contact:

Principal Investigator
Alexander T Sandhu, MD, MS
Stanford University

Backup Contact:


Location Contact:

Stanford, California 94066
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source:

Date Processed: June 21, 2021

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on The form below is not enabled.