Clinical Trial 15340

Houston, TX 77062

Study Summary:

A phase lll, multi-center, randomized, double-blind, placebo-controlled, parallel group study of two dosing regimens of Fostamatinib Disodium in Rheumatoid Arthritis patients with inadequate response to a TNF-alpha antagonist.

Qualified Participants Must:

• Be at least 18 years of age
• Have a diagnosis of RA
• Be receiving treatment with Methotrexate for at least 6 months
• Have received a single TNF-a antagonist discontinued due to lack of efficacy, more than one if discontinued due to safety or tolerability
• Have not received rituximab
• Have not received abatacept
• Have not received tocilizumab

Qualified Participants May Receive:

Compensation for time and travel.

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.