Clinical Trial 1562

Scottsdale, AZ 85251

Study Summary:

This is a 6-month randomized, double-blind, parallel-group, multicenter, placebo-controlled phase II study to compare anti-asthmatic effect and safety of Esomeprazole (Nexium) 40 mg twice daily or 40 mg once daily with placebo in adults with asthma.

Qualified Participants Must:

• Be between 18 and 70 years of age with diagnosis of asthma for at least 6 months
• Have symptoms of asthma during run-in
• Have at least a 3 months history and present symptoms of 1 or more of the following: burning feeling behind breastbone, pain behind breastbone, acid taste in the mouth
• Not have clinically relevant abnormalities
• Not have a smoking history of greater than or equal to 10 pack-year
• Not have had previous surgery on the esophagus or the stomach

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.