Summary:
Osteoarthritis is the most common kind of arthritis which happens when the cartilage that protects the end of your bones wears down. This leads to symptoms like pain and stiffness. Osteoarthritis can affect any joint in your body, including knees and hips.
TANGO is a clinical research study for osteoarthritis pain. The TANGO studies are for people with pain from osteoarthritis in a hip or knee. These studies will assess the effects of Tanezumab, the investigational study drug, to find out how safe and effective it is in treating osteoarthritis pain. Arthritis affects millions of people worldwide.
Tanezumab will be compared with either a placebo (dummy drug) or an NSAID depending on the study. A placebo looks like the study drug but does not contain any drug. NSAIDs are a group of medications that relieve pain. NSAIDs also help to reduce inflammation and lower fevers.
Qualified Participants Must:
• Be 18 years of age or older
•
Be diagnosed of osteoarthritis of knee or hip
•
Currently taking one of the following medications in stable dosage at least 30 days prior to screening day:
Naproxen 500mg/ day to 1000mg/day
Celebrex 200mg/day or combination of 100mg/day but twice a day
Diclofenac, such as Voltaren, Solaraza, Cambia, Zipsor, Pennsaid, Flector, Cataflam at least 100 mg/day to 150mg/day
•
The study doctor has the final determination for study enrollment based on medical review
Qualified Participants May Receive:
• Complimentary investigational drug Tanzumab or placebo, physical examination, x-rays, MRI, and Bone Density (selected patient may be required)
• Participant may receive $75 per study clinic visit and $25 per each procedure visit such as X-rays, MRI, and Bone Density.