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Clinical Trial 45253

Iowa City, IA 52242


Summary:

Exicure Advanced Squamous Cell Skin Cancer Research Study

The advanced squamous cell skin cancer research study will evaluate how safe and tolerable a new investigational treatment is both alone and in combination with cemiplimab in adults who qualify. The research study is open label and non-randomized. This means that you will know information about the active ingredients in the investigational treatment.

Eligible study participants:

  • Are at least 18 years or older
  • Are diagnosed by a doctor with advanced or metastatic cutaneous squamous cell carcinoma (also known as advanced squamous cell carcinoma of the skin) and had your disease worsen on the standard treatment (cemiplimab (Libtayo®) or pembrolizumab (Keytruda®) as the most recent treatment
  • Have tumors on or under your skin, or in lymph nodes
  • Do not have other cancers at the same time
  • Do not have active or documented history of an autoimmune disease or syndrome requiring steroid or immunosuppressive treatment

Additional study requirements and exclusions may apply. A study representative will discuss these with you during the screening period.


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.