Expired Study
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Clinical Trial 4578

Sandy, UT 84094


Study Summary:

We are currently conducting a study to compare safety and effectiveness of Extended Release study medication (Aciphex ER) to Nexium ("the purple pill") for reduction of esophageal erosions caused by GERD.

Aciphex and Nexium are both medications that are approved for GERD. The study medication Aciphex ER is not yet approved.

No placebo. All subjects receive one type of active medication plus a placebo pill.

If your Heartburn and/or acid indigestion is left untreated, they can cause erosions on the esophagus.

This study is a up to 8 week study for subjects that have moderate to severe gastro-esophageal erosions.

Erosions are diagnosed by study provided Upper GI scope procedure.


Qualified Participants Must:

• Be age 18-75 years of age
• Be able to attend up to six study visits over a 10-14 week time period
• Have a history of GERD symptoms for three months before study start
• Have heartburn at least two (2) days a week for one month (1 mo.) prior to study start


Qualified Participants May Receive:

Study related medical and laboratory exams, including upper GI scope procedures at no cost. Study medication provided. Time and travel compensation of $50.00 for each study visit completed.


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.