Clinical Trial 45973

Garden Grove, CA 92845


The clinical trial is a Phase 2, double-blind, randomized, placebo controlled study in Major Depressive Disorder (MDD) participants currently treated with antidepressant therapy. The objective of the study is to assess CLE-100 for the treatment of MDD in participants currently treated with standard antidepressant therapy.

  • Male or female between 18 to 60 years of age
  • Primary diagnosis of MDD, without psychotic features according to DSM-5 and supported by the Mini International Neuropsychiatric Interview (MINI)
  • MADRS score of at least 18 at Screening
  • Treatment with stable dose of the current antidepressant therapy for at least 4 weeks for the current major depressive episode (MDE)
  • Body mass index (BMI) between 18 and 40 kg/m2, inclusive
  • Is able and competent to read and sign the informed consent form (ICF).

Qualified Participants May Receive:

Monetary compensation for participating.

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.