Clinical Trial 45984

Garden Grove, CA 92845


The purpose of this study is to investigate the effect of Lu AG06466 after multiple doses of 40 mg in patients with PTSD

  • The subject has a BMI of ≥18.5 and ≤32 kg/m2.
  • The subject has PTSD, diagnosed according to Diagnostic and Statistical Manual Diploma in Social Medicine-5 (DSM-5), and confirmed by the Mini International Neuropsychiatric Interview (MINI).
  • The subject has a Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) total score ≥28 at screening and baseline.
  • The subject has alterations in arousal and reactivity, confirmed on CAPS-5.
  • The subject has ongoing sleep disturbances, confirmed on CAPS-5.
  • The subject is willing to discontinue all prohibited medications during the study and to complete a washout of psychotropic medication during the washout period.
  • The subject does not have any MRI contraindications.

Qualified Participants May Receive:

Monetary compensation for participating.

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.