Clinical Trial 4627

New York, NY 10032


Study Summary:

Recently, some small studies have suggested that gastric bypass surgery may be useful in the treatment of diabetes and may be better than standard medical therapy (oral medications, insulin injections, etc) in the treatment of diabetes.

The purpose of this study is to assess the short term effects of Roux-en-Y gastric bypass on type 2 diabetes and to determine whether intensive medical therapy or surgical therapy combined with intensive medical therapy is better in the treatment of patients with type 2 diabetes and moderate obesity. All study participants will receive comprehensive medical management of their diabetes including nutritional education for two years at no cost. If randomized to the surgical arm, costs also will be covered for the surgical procedure.


Qualified Participants Must:

• Have Type 2 Diabetes for 6 months or longer
• Be at least 40 but no more than 75 lbs overweight (BMI 30-34.9)
• Be 35-67 years of age
• Be willing to be randomized to medical treatment group OR laparoscopic gastric bypass


Qualified Participants May Receive:

All study participants will receive comprehensive medical management of their diabetes including nutritional education for 2 years at no cost.


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.