Clinical Trial 49259

Birmingham, AL 35294


<b>Major Depressive Disorder (MDD) - Multiple Locations in the US</b>

The TERPSIS Study is evaluating the safety of a once-weekly oral investigational medication and whether it improves the lack or loss of interest in usually pleasurable activities in participants with MDD.

The total length of the TERPSIS Study is approximately 20 weeks. This includes a 4-week screening period to make sure the research study is a good match for you, an 8-week treatment period in which you will receive either the investigational medication or placebo, and an 8-week follow-up period to check on your health after stopping the assigned study treatment.

Individuals will be evaluated to determine their eligibility to participate. Each patient who qualifies will receive the investigational medication or the placebo, as well as study-related medical exams and study-related laboratory tests, all at no cost. If participants in the TERPSIS Study are currently on antidepressant medication(s), they will be able to stay on their current antidepressant(s) during the research study.

Eligibility Criteria:
For the TERPSIS Study, eligible participants must:

  • Be 18 to 65 years of age (inclusive)
  • Have a confirmed diagnosis of MDD
  • Be currently on or have previously been on an antidepressant medication(s)
  • Not be pregnant or breastfeeding or planning to become pregnant during the study

Other protocol-defined inclusion and exclusion criteria may apply.

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.