Clinical Trial 49360

Los Angeles, CA 90095


How do the immune system and anxiety affect brain and behavior? This NIH-funded study will investigate how the immune system may influence brain and behavior in the presence of anxiety. Participants will receive an injection of endotoxin (a substance that activates the immune system and can cause flu-like symptoms that last up to several hours). Participants complete questionnaires and computer tasks, provide blood samples, and complete a 1-hour fMRI scan. Participants will receive monetary compensation and medical examinations.

Qualified Participants Must:

• Be between the ages of 60-80
• Have elevated anxiety symptoms
• Be a non-smoker
• Be in good general health

Qualified Participants May Receive:


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.