If you suffer from chronic pain or aching in your knee, you may have osteoarthritis (OA) - a painful joint condition that can interfere with all aspects of daily life. When initial treatments fail to relieve the pain, many sufferers are faced with an unsettling future - increasing use of pain medications, invasive knee surgery, or continued suffering.
The study lasts about 6 - 7 months. Following an initial Screening Visit to confirm if you are eligible to join the study, you will begin the Treatment Period (about 6 weeks). During the Treatment Period, you will visit your study doctor’s office twice per week for 6 weeks to receive the study injection. Once the Treatment Period has ended, you will enter a Follow-Up Period (about 5 months) to understand how the treatment worked for you. The Follow-Up Period involves 5 total visits to your study doctor’s office, each about 1 month apart.
Criteria:Be over 18 years old
Have knee pain
No records of fibromyalgia, Rheumatoid Arthritis, Gout
No Current treatment with anticoagulants or antiplatelet drugs, excluding aspirin ≤100 mg/day.
No Documented or reported history of increased bleeding in the absence of anticoagulant or antiplatelet drugs or prior history of major bleeding episode in the presence of anticoagulant or antiplatelet therapy.
No Currently active or recent history (within preceding 12 months) of a gastric or duodenal ulcer, or suspicion of gastrointestinal tract bleeding.
Can not be using Aldosterone antagonists, Amiloride, Angiotensin-converting enzyme inhibitors, Angiotensin II receptor antagonists, Candesartan, canrenoate potassium, Captopril, drospirenone, enalapril, eplerenone, lisinopril, Lithium, losartan, Potassium chloride, Potassium salts, Potassium-sparing diuretics, Spironolactone.