Clinical Trial 5270

Fair Oaks, CA 95628

Study Summary:

We are currently conducting a phase 3, double-blind, randomized, factorial, efficacy and safety study of TAK-491 plus Chlorthalidone fixed-dose combination in subjects with moderate to severe Hypertension.

Qualified Participants Must:

• Be 18 years of age or older
• Be willing to washout current high blood pressure medication
• Have post washout Systolic BP between 150 and 180mm Hg
• Be treatment naive with systolic BP between 160 and 190mm Hg

Qualified Participants May Receive:

Blood pressure monitoring, laboratory tests, physical exams, electrocardiograms (ECGs), office visits, and study medication

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.