Expired Study
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Clinical Trial 5464

Brighton, MA 02135


Study Summary:

The study is examining the effects of adding a sleep aid to an antidepressant in women with depression, anxiety, and insomnia. It involves taking an FDA-approved antidepressant for 10 weeks as well as a sleep aid or placebo. There are four MRI scans at McLean Hospital in Belmont, MA and four visits at St. Elizabeth's Medical Center.


Qualified Participants Must:

• Be female and between the ages of 18 and 55
• Regularly menstruating
• Meet criteria for major depression
• Not have a medical condition or take a medication that affects the GABA or glutamate system
• Be currently experiencing insomnia
• Not currently be taking antidepressant medication


Qualified Participants May Receive:

Study medications are provided free of charge and participants receive up to $600.


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.