Clinical Trial 5659

Boston, MA 02118


Study Summary:

This study looks at how testosterone affects a woman's mind and body. Testosterone is commonly thought of as a "male hormone," however women produce it as well.

Half of a woman's testosterone is made in her ovaries and half made in her adrenal glands (glands on top of her ovaries). When a woman has her ovaries and uterus removed she has significant decrease in the testosterone levels in her blood.

Testosterone can affect many things including sexual function, mood, energy level, muscle size and strength, how a person thinks, and how the body handles sugar.

This study will look at how testosterone injections, given in combination with estrogen patches, influence these various functions.

This study lasts approximately 14 months, has 40 visits that are weekly to monthly on Monday-Friday from 8am-3pm.


Qualified Participants Must:

• Be women aged 21-60
• Have had a hysterectomy (with or without the removal of their ovaries) over 3 months ago
• Not have a history of breast, ovarian or uterine cancer
• Not have a history of blood clots in their legs or lungs


Qualified Participants May Receive:

During the study participants will be paid different amounts with each study visit. The purpose of these payments is to compensate for transportation, time and effort. If you complete the entire study you will be paid $1000.


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.