Clinical Trial 5872

Atlanta, GA 30342


Study Summary:

The PRECISION Study is a research study that will compare 3 approved medicines commonly used to treat pain in people who have osteoarthritis (OA) or rheumatoid arthritis (RA) and have or are at risk for heart disease. The 3 approved medicines included in the study are celecoxib (brand name Celebrex), ibuprofen (brand names include Advil, Medipren, Motrin, and Nurprin), and naproxen (Aleve, Anaprox, Naprelan, and Naprosyn). The PRECISION Study will help doctors learn more about long-term heart safety of these medicines. The study will help provide the information doctors need to choose the most appropriate pain reliever for their patients who have OA or RA and have or are at risk for heart disease.


Qualified Participants Must:

• Be 18 years of age or older
• Have had OA or RA for at least 6 months
• Have been prescribed regular medication for your OA or RA pain for at least 6 months
• Have or be at high risk for heart disease (for example, if you've had a heart attack or stroke, or have diabetes)


Qualified Participants May Receive:

Study-related check-ups and study medication at no charge. Obtain study-related medical care during the study. Help others by contributing to medical research.


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.