Clinical Trial 7226

Hoover, AL 35216

Study Summary:

The goal of this study is to compare an investigational drug, icatibant, to a placebo on the time to symptom relief of an acute HAE attack using a tool known as a Visual Analog Scale (VAS), which is a scoring device that you will complete. This study will be conducted in patients with type I and II HAE who are experiencing acute skin, abdominal (stomach), or laryngeal (throat or airway) attacks.

Qualified Participants Must:

• Be 18 years of age or older
• Have a documented diagnosis of type I or II HAE
• There are several other ways the study team will evaluate you, in addition to this brief list

Qualified Participants May Receive:

After signing the Infomed Consent at your first visit and being documented as a type I or II HAE patient, you will be evaluated at your next HAE attack. The evaluation will determine if the attack qualifies for treatment through an injection under the skin of your abdomen. All treatments will be performed in the doctor's office or hospital at no cost to the patient. The study team will reimburse you for time and travel.

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.