Clinical Trial 7337

Jonesboro, AR 72401

Study Summary:

A clinical study to assess the effectiveness and safety of Teplizumab (MGA031), in children and adults with recent-onset Type 1 Diabetes Mellitus.

Qualified Participants Must:

• *Diagnosis of diabetes mellitus according to the American Diabetes Association (ADA) criteria *Written informed consent obtained from the subject. *Diagnosis to have occured within the previous 10 weeks (**note to sponsor & IRB we understand there is a 12 week window between diagnosis and study day 0, therefore we would like to show a shortened window so that we as a site have ample time to fully enroll the subject before the expiration window) *Currently receiving insulin therapy *8–35 years old *Body weight > 79 lbs *Willing to forego other forms of experimental treatment during the study

Qualified Participants May Receive:

Study medication and compensation for their time and travel

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.