Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials!!

Clinical Trial 9380

Burbank, CA 91505


Study Summary:

The purpose of this study is to compare the analgesic efficacy and safety of ABT-652 administered twice daily (BID) to placebo in subjects with osteoarthritis (OA) of the knee.


Qualified Participants Must:

• Have a history of OA of the knee joint and meeting ACR Clinical and Radiographic criteria
• Have pain score as required by the protocol at screening and baseline
• Be willing to washout of analgesics and to follow treatment plan, visit schedules and study procedures
• Not have a history of sensitivity to histamine medications, acetaminophen (paracetamol), or non-steroidal anti-inflammatory drugs (NSAIDs)
• Not have active gastrointestinal (GI) disease, GI bleeding or GI ulceration, or history of GI bleeding or GI ulceration in the last 6 months
• Not have a history of major psychiatric disorders
• Not have a diagnosis of rheumatoid arthritis, autoimmune disorder, arthritis other than osteoarthritis involving the study joint, or other painful syndrome that could interfere with the assessment of pain at the study joint
• Not have any cardiac, respiratory, neurological or other medical condition or illness that is not well controlled with treatment


Qualified Participants May Receive:

Study drug, study-related medical exams, and study-related laboratory tests.


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.