Background:

This case study focuses on efforts to find participants for a virtual, at-home clinical trial aimed at studying asthma. The trial recruitment took place over a ten-month period and utilized both email and SMS outreach to ClinicalConnection’s database of members interested in asthma clinical trials.

Objective:

This case study's main objective was to engage a substantial number of participants across the United States who met the trial's eligibility criteria in an efficient and timely manner.

Recruitment Completion:

Consented: 92 members formally consented to participate in the trial.

Randomized: Finally, 32 members were randomized and successfully enrolled in the clinical trial.

Recruitment Challenges:

This trial also allowed for children to participate. Pediatric clinical trial recruitment has proved to be difficult for almost all conditions and indications.

Discussion:

The email and SMS outreach strategy employed in this case study yielded notable results in terms of participant engagement and enrollment for the clinical trial.

With 4,456 members expressing interest and signing up for the study through the partner's online pre-screener, the outreach campaign demonstrated a significant level of effectiveness, accounting for over 10% of the contacted members. This high level of initial engagement underscores the importance of targeted and personalized communication methods in recruiting participants for clinical trials.

Out of the total sign-ups, 1,620 members were deemed eligible for the study after undergoing further review. This step highlights the necessity of thorough screening processes to ensure that enrolled participants meet the necessary criteria for the trial.

A crucial aspect of the enrollment process involved obtaining medical records from interested participants to verify their eligibility. While 289 members signed agreements for their medical records to be retrieved, successful acquisition was achieved for 240 members. This phase emphasizes the importance of establishing clear and efficient procedures for obtaining and verifying participant information.

Subsequently, 92 members formally consented to participate in the trial, indicating a significant level of commitment from the eligible participants. This stage reflects the importance of transparent communication and informed consent in maintaining ethical standards throughout the recruitment process.

Finally, 32 members were randomized and successfully enrolled in the clinical trial. This final step underscores the culmination of efforts in participant recruitment and highlights the successful outcome of the outreach strategy in achieving the trial's enrollment objectives.

Analysis and Conclusion:

The recruitment campaign demonstrated significant success in engaging potential participants for the asthma clinical trial and enrolling a substantial number of participants into the trial. The campaign achieved its primary goal of finding enough participants for our partner to end the recruitment period on time. The effectiveness of the multi-channel approach, particularly utilizing email and SMS outreach, is evident in the high number of sign-ups and successful engagement at various stages of the screening process.

Overall, the case study demonstrates the effectiveness of email and SMS outreach in engaging potential participants, guiding them through the enrollment process, and ultimately facilitating successful enrollment in the clinical trial. These findings underscore the significance of strategic communication approaches in overcoming recruitment challenges and ensuring the success of clinical research endeavors.