Study Summary:
A 24 week study to evaluate the effect of (GW685698)/Vilanterol (GW642444) inhalation powder delivered once daily via Novel Dry Powder Inhaler on patients with arterial stiffness (hardening of the arteries) compared with placebo and Vilanterol in patients who suffer from chronic obstructive pulmonary disease (COPD).
Qualified Participants Must:
Be at least 40 years of age
Have a current or prior history of greater than or equal to 10 pack-years of cigarette smoking
Not have a Lung Resection within 12 months prior to screen or having had a lung transplantation
Not have current or severe heart failure
Not use Oxygen more than 12 hrs/daily
Not have a complete right or left bundle branch block
Qualified Participants May Receive:
Study Medication at no cost, lab work, pulmonary function tests and compensation for time and travel.