Summary:
The SYNERGY study is for people who have symptoms of overactive bladder (OAB) with uncontrolled urine loss.
OAB causes a frequent and strong urge to urinate. When this urge is followed by sudden or uncontrolled leakage, it is considered a form of OAB called “urinary incontinence.” People who have this form of OAB experience moments throughout the day – and night – when the urge is so sudden and strong that they have difficulty making it to the bathroom in time. The SYNERGY study is for people who have this form of OAB.
If you are not being treated for these symptoms – or if your current medication does not provide enough relief or is causing unwanted side-effects – the SYNERGY study may be an option for you.
The SYNERGY study represents a new direction in research for overactive bladder (OAB). It is evaluating an investigational combination of two drugs for OAB to see if, when taken together, they provide more relief than when taken on their own. It is also looking to determine if the two drugs, when taken together, have fewer side-effects than when taken separately.
One Combination. Two Pathways.
The two drugs have been shown to be well-tolerated and effective when taken on their own. Each drug targets symptoms through a different process, or pathway:
One drug relaxes the bladder muscle, reducing involuntary contractions that cause uncontrolled leakage; AND
One drug relaxes the bladder muscle during filling, improving storage capacity
One drug belongs to a new class of drugs that is designed to treat OAB in a different way than other treatments. Researchers are looking to determine if this dual approach may be effective in relieving symptoms.
If you experience a frequent and sudden urge to urinate, followed by leakage or loss of bladder control, you may be eligible to participate in this 6 month study and received $75 per completed study visit, total of 6 study visits.
Qualified Participants Must:
• Be 18 years of age, or older
•
Be willing and able to complete the micturition diary and questionnaires correctly and able to measure his/her vital signs at home at stipulated time points, using the device provided by the study personnel, and to adequately record the readings
• patient has symptoms of “wet” OAB (urinary frequency and urgency with incontinence) for at least 3 months
Qualified Participants May Receive:
Complimentary health Screenings, lab results, and $75 per visit.