Summary:
If you have diabetic kidney disease, the SONAR clinical research study may be an option for you.
About diabetic kidney disease
People with type 2 diabetes have high blood sugar. Kidneys act like a filtering system that removes excess sugar and other waste products from the blood. But when blood sugar gets too high the filters in the kidneys have to work too hard and can become damaged.
People with diabetes who have damaged kidneys often develop a condition called proteinuria, which means they have too much protein in their urine. Too much protein in the urine is a sign of kidney disease.
What is the purpose of the study?
The purpose of the study is to evaluate the safety and effectiveness of an investigational drug in patients with diabetic kidney disease.
The study will compare the investigational medication with a placebo to see if taking it is any different than taking a placebo. Placebo is a tablet that looks like the investigational medication but has no active ingredient in it.
Who can participate?
You may be eligible for the study if you:
- Are 18–85 years of age
- Are male or a post-menopausal female
- Have type 2 diabetes and kidney disease
- Are being treated with a renin-angiotensin system (RAS) inhibitor
- Do not have a history of heart failure
There are other eligibility criteria that the study doctor will review with you. If you meet the criteria and choose to participate in the study, you can leave the study at any time for any reason.
How long will the study last?
Study participation may last up to approximately 48 months and include up to 32 study visits to the research center. At study visits, you will have tests and evaluations to monitor your health.