Summary:
A multicenter, randomized, double-blind, placebo-controlled, parallel-group study of subcutaneous MOA-728 for the treatment of Opiod-Induced Constipation in subjects with chronic non-malignant pain.
Qualified Participants Must:
• Be 18 years of age or older
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Be able to sign informed consent
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Have a history of chronic pain with documentation within the last 2 months
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Stable medical status
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Have a history of constipation due to opiod use for at lease 1 month prior to visit
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Willing to discontinue pre-study laxative therapy and use only the study-permitted rescue laxative.
Qualified Participants May Receive:
Compensation for time and travel, study related care, and study related medication for the indication under study.