Clinical Trial 39668

Methuen, MA 01844


Summary:

WORRIED ABOUT MEMORY LOSS?

Many of us notice that our memory gets worse as we get older. Usually, this is just a natural part of aging. However, memory loss that starts to impact daily life could be an early sign of Alzheimer's disease.

The TANGO Study is for people who are beginning to experience problems with memory (called mild cognitive impairment) and want to find out why, as well as for those who have been diagnosed with mild Alzheimer’s disease. The study is evaluating the potential effectiveness of an investigational drug to see if it may help slow or reduce memory problems.

OVERVIEW OF THE TANGO STUDY

The hallmark of Alzheimer’s disease is the development of plaques and tangles of certain types of proteins in the brain. The TANGO Study is evaluating the safety, dosing, and effectiveness of an investigational drug to see if it has the potential to be a treatment in people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease.

The investigational drug is designed to target the tau protein, which is one of the key proteins that build up in the brain and cause tangles in people with Alzheimer’s disease. Researchers are evaluating the investigational drug to see if when taken early, it may potentially help reduce the spread of tau in the brain—and if it may potentially slow the progress of the disease.

    KEY ELIGIBILITY CRITERIA

    • Men and women 50–80 years old
    • Diagnosed with mild Alzheimer’s disease or early memory problems
    • No other significant / uncontrolled medical issues

    ALL ELIGIBILE STUDY PARTICIPANTS WILL RECEIVE AT NO COST:

    • Comprehensive study-related health evaluations and assessments
    • Study-related drugs, visits, and care
    • Travel assistance to and from study visits
    • Opportunity to take part in a long-term extension study

    SEE IF YOU OR A LOVED ONE MAY BE ELIGIBLE


    Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.