Click image to enlargeCytomegalovirus (CMV) is a virus that can infect people of all ages. Most people never have symptoms of CMV. This is because a healthy person’s immunesystem can usually fight offthe virus. However, the virus can cause health problems for some babies whose mothers become infected with CMV while they are pregnant.
What is the purpose of the study?
- The V160-002 study is testing a vaccine to see if it can prevent CMV infection in women who have not already been infected with CMV. This study is also testing how your body handles the vaccine, and if the vaccine is safe.
What is the study vaccine?
- This study is testing a vaccine called V160. Researchers are testing the safety of the vaccine and how well it works to prevent CMV infection in women who may eventually have children. Most babies born with CMV don’t have any symptoms. However, CMV can cause health problems at birth in some babies.
These can include:
• vision problems
• hearing problems
• issues with the nervous system
Even babies who have no CMV symptoms when they are born can develop hearing loss when they get older
A vaccine to prevent women from getting a CMV infection may be able to stop the spread of CMV from mothers to babies. The V160 vaccine is not approved by the United States Food and Drug Administration (FDA). Not everyone who volunteers for this study will receive the V160 vaccine. Some volunteers will get a placebo. Both the V160 study vaccine and placebo are injections, but the placebo contains no medicine. Using a placebo may let researchers learn more about how well the study vaccine works.