Clinical Trial 41842

Tampa, FL 33613


Study Summary:

Study 41842 Flyer
Click image to enlarge

A research study comparing the effectiveness of three standard treatments for patients with Treatment Resistant Depression.  The standard treatments being compared include:

- Adding aripiprazole to current treatment

- Adding rTMS (repetitive transcranial magnetic stimulation) to current treatment

- Switching current antidepressant medication to venlafaxine extended-release or duloxetine

The study will take up to 12 weeks/7 visits to complete.  If randomized to receive rTMS, you will have up to 26 additional rTMS treatment visits over the course of the study.



To be eligible for this study, participants must:

- be 18-80 years old

- diagnosed with Major Depression with less than 50% of symptom improvement on current medication

- currently taking an antidepressant medication


Qualified Participants May Receive:

All study participants will received study-related medication or treatment, study visits, and study related procedures at no cost. 


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.