Clinical Trial 42617

Columbus, OH 43215


GERD/Heartburn Study

Do you have Heartburn or GERD symptoms despite taking daily medications?

The purpose of the study is to determine how well an investigational medication works when given with a standard dose of a Proton Pump Inhibitor for patients with GERD who continue to have persistent symptoms such as heartburn and regurgitation. The active ingredient in the study drug is Welchol or Colesevelam (used to lower cholesterol and treat type 2 diabetes).  If you qualify to be in this study, you may continue to take your proton pump inhibitor.

The study is double-blinded which means that neither you nor the study staff knows what treatment you would be receiving but in the case of an emergency that information would become available. If you are interested and volunteer to be in this study, you would come to the study center for up to 5 visits over the course of 17 weeks. There is a chance of you receiving a placebo instead of the study drug, which will neither benefit nor harm you.

Visits may include physical exams, blood pressure, labs, and questionnaires. You will also complete an electronic diary at home to record your ongoing symptoms. Study required medical procedures and medication are provided at no cost to you. You will be compensated for your time and travel.

Qualified Participants May Receive:

Qualified volunteers will receive at no cost:
•  Study medication
•  Study-related care from a local doctor
•  Reimbursement for your time and travel up to $1,005.00

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.