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Clinical Trial 42763

State College, PA 16801


How Much of Your Life Revolves Around Knee Pain?
If you or a loved one are suffering from chronic knee pain due to osteoarthritis and are seeking new care options, you may be eligible to participate in the AP-013 OA Trial. This clinical research study is evaluating the efficacy and safety of a new, investigational treatment for osteoarthritis of the knee. Qualified participants will receive study-related care at no cost.

See if you or a loved one qualify!

Participation Requirements
You or a Loved One May Qualify If You:

  • Are between 40-85 years old
  • Have been diagnosed with severe osteoarthritis of the knee
  • Have been experiencing chronic knee pain due to osteoarthritis of the knee for at least 6 months
  • Are ambulatory
  • Are willing and able to discontinue NSAID use for 48 hours prior to scheduled clinical efficacy evaluations
  • Have no history of inflammatory or crystal arthropathies, acute fractures, aseptic necrosis or joint replacement in the affected knee.
  • Have no history of isolated patella femoral syndrome, also known as chondromalacia
  • Do not have another disease or condition interfering with the target knee
  • Do not have any other pain that might interfere with the assessment of index knee pain
About the Clinical Research Study
This study is testing the safety and effectiveness of a new investigational treatment for patients with severe knee pain due to osteoarthritis. Your participation in the study will span 24 weeks, including 4 visits to the study clinic and 7 phone conversations with study staff.

Over the course of the study, you will receive either the active or placebo version of the investigational drug and have doctors monitor your health and progress through study-related tests and assessments.

See if you or a loved one qualify!

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.