Summary:
The Sparkle 1501 Study for Narcolepsy with Cataplexy
Narcolepsy is a sleep disorder that causes persistent sleepiness throughout the day, disrupting the brain’s ability to regulate sleep-wake cycles. Approximately 60-70% of people diagnosed with narcolepsy also experience cataplexy. Symptoms of cataplexy include sudden loss of muscle tone often triggered by a strong emotion like excitement or laughter.
Further development is needed in treating sleep disorders.
What is the purpose of the Sparkle 1501 Study?
This clinical study is testing an investigational drug (TAK-994) to see how safe and tolerable it is and how it affects a person’s narcolepsy symptoms.
Is study participation an option for me?
You may qualify if you:
- Are 18–65 years old
- Have been diagnosed with narcolepsy with cataplexy
- Experience excessive daytime sleepiness
- Experience more than or equal to 4 episodes of cataplexy/week
- Meet additional requirements as determined by a screening process
A study doctor and staff can explain to you in greater detail other requirements and eligibility criteria you would have to meet to participate in the study. Travel support and compensation for study participation may be available.