Clinical Trial 43373

Garden Grove, CA 92845


This study will be conducted to evaluate the efficacy, safety, and tolerability of AVP-786, as compared with placebo, for the treatment of negative symptoms of schizophrenia.

Inclusion Criteria:

  • Participants who meet the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-V) diagnostic criteria for schizophrenia confirmed by the Mini International Neuropsychiatric Interview (M.I.N.I) Version 7.0.2
  • Participants must meet Positive and Negative Syndrome Scale (PANSS) criteria
  • Participants currently receiving a second-generation atypical antipsychotic drug (SGA) are eligible provided they are on a stable dose

Exclusion Criteria:

  • Participants with current major depressive disorder (MDD)
  • Participants with pseudo-parkinsonism secondary to their ongoing antipsychotic medication
  • Participants currently using anticholinergic medications
    • Participants recently hospitalized as in-patients

Qualified Participants May Receive:

Monetary compensation and study-related care at no cost to the participant. 

Available At:

CNS - Collaborative Neuroscience
12772 Valley View St.
Garden Grove, CA 92845
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If you or someone you care for is interested in participating and lives within 50 miles of the location shown, please complete the form below and click 'Submit'

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.