Clinical Trial 44562

New York, NY 11411


Summary:

Hypertension is one of the leading causes of morbidity and mortality in the industrialized world, attributed mostly to modifiable lifestyle factors. Aspects that are controlled by patients include physical activity, smoking, alcohol consumption, and nutrition.

The DASH (Dietary Approach to Stop Hypertension) diet is a proven effective intervention in lowering blood pressure in multiple populations. In this proof of concept study, volunteers with untreated stage 1 hypertension, defined as mild high blood pressure with numbers in the range of 130 - 139 over 80 - 89, will receive a DASH-based menu during 5 days of hospitalization, during a weekend at home where they will continue the menu, another 5 days as inpatients, followed by a weekend at home on the same menu, and the return to the inpatient unit for an additional day for final testing.

Throughout the intervention period, participants will be followed clinically and undergo repeated laboratory testing. The aim of this project is to characterize changes in urine electrolytes and exosome protein abundance pattern during nutritional changes, shifting from a "westernized diet" to a DASH diet.


Qualified Participants Must:

• Have untreated mild or high blood pressure (currently not taking medication)
• Be between the ages of 18 and 60
• Identify as Black/African American or Caucasian Eat a typical American/Western diet
• Be normal weight or overweight according to BMI calculator (not obese)
• Be able to commit to a 14-day inpatient stay (weekends at home)


Qualified Participants May Receive:

Compensation is provided ; All meals (DASH diet) provided 


Available At:

The Rockefeller University
1230 York Avenue
New York, NY 11411
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Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.