Summary:
This study is being conducted for people who have elevated lipids (fats) called triglycerides and cholesterol in your blood and are being treated with a type of drug called a statin. Elevations of lipids puts people at risk for a heart attack, stroke and angina (chest pain related to the heart).
This study will explore a new investigational drug, vupanorsen, that can lower the levels of lipids in the blood. An investigational drug is one that has not been shown to be a proven treatment and is currently not approved for sale in any country. Vupanorsen works by lowering triglycerides and cholesterol levels. It works by reducing the production of angiopioetin like 3 (ANGPTL3) protein in the liver. ANGPTL3 works as a regulator of triglycerides and cholesterol, and by decreasing ANGPTL3 activity, vupanorsen decreased levels of these lipids in the blood.
Qualified Participants Must:
• Be at least 40 years of age
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Taking a statin or intolerant to statins
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Have Triglyceride levels between 150-500
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Currently not taking a blood thinner or have any implanted devices (such as pacemaker)
Qualified Participants May Receive:
- Study related care such as blood work and EKG
- Compensation for time and travel expenses
- Physical performed by a board certified physician