Clinical Trial 45640

Winter Haven, FL 33880


This study is being conducted for people who have elevated lipids (fats) called triglycerides and cholesterol in your blood and are being treated with a type of drug called a statin. Elevations of lipids puts people at risk for a heart attack, stroke and angina (chest pain related to the heart).

This study will explore a new investigational drug, vupanorsen, that can lower the levels of lipids in the blood. An investigational drug is one that has not been shown to be a proven treatment and is currently not approved for sale in any country. Vupanorsen works by lowering triglycerides and cholesterol levels. It works by reducing the production of angiopioetin like 3 (ANGPTL3) protein in the liver. ANGPTL3 works as a regulator of triglycerides and cholesterol, and by decreasing ANGPTL3 activity, vupanorsen decreased levels of these lipids in the blood.

Qualified Participants Must:

• Be at least 40 years of age
• Taking a statin or intolerant to statins
• Have Triglyceride levels between 150-500
• Currently not taking a blood thinner or have any implanted devices (such as pacemaker)

Qualified Participants May Receive:

- Study related care such as blood work and EKG

- Compensation for time and travel expenses

- Physical performed by a board certified physician

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.