Clinical Trial 45640

Winter Haven, FL 33880


Summary:

This study is being conducted for people who have elevated lipids (fats) called triglycerides and cholesterol in your blood and are being treated with a type of drug called a statin. Elevations of lipids puts people at risk for a heart attack, stroke and angina (chest pain related to the heart).

This study will explore a new investigational drug, vupanorsen, that can lower the levels of lipids in the blood. An investigational drug is one that has not been shown to be a proven treatment and is currently not approved for sale in any country. Vupanorsen works by lowering triglycerides and cholesterol levels. It works by reducing the production of angiopioetin like 3 (ANGPTL3) protein in the liver. ANGPTL3 works as a regulator of triglycerides and cholesterol, and by decreasing ANGPTL3 activity, vupanorsen decreased levels of these lipids in the blood.


Qualified Participants Must:

• Be at least 40 years of age
• Taking a statin or intolerant to statins
• Have Triglyceride levels between 150-500
• Currently not taking a blood thinner or have any implanted devices (such as pacemaker)


Qualified Participants May Receive:

- Study related care such as blood work and EKG

- Compensation for time and travel expenses

- Physical performed by a board certified physician


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.