We are currently looking for participants who are not taking any medication for depression, but still having moderate to severe depression symptoms. The purpose of this study is to test an investigational drug in combination with an antidepressant to determine if it reduces depressive symptoms in patients with MDD more than an antidepressant alone.
This is a double-blind study, once you are enrolled into the study, you will be randomly (like flipping a coin) assigned to the investigational drug or a placebo. A placebo looks like the study drug but does not contain any active ingredients.
This study involves a screening visit, similar to an annual check up, followed by a 14-day treatment and a 28 day antidepressant therapy continuation period.
Several visits will require coming in twice a week and each visit lasts about 2 hours.