We are doing this study (the ZEUS study) to see if the new study medicine, ziltivekimab, can be used to treat people with cardiovascular disease, chronic kidney disease and inflammation. The ZEUS study will see if ziltivekimab can reduce the risk of having cardiovascular events (for example heart attack and stroke).
The term cardiovascular disease refers to several conditions that affect your heart and blood vessels. These conditions include myocardial infarction (also known as heart attack), stroke (also known as brain attack) and peripheral arterial disease (also known as poor circulation). People with cardiovascular disease and chronic kidney disease often have inflammation.
Inflammation is a critical process for wound healing and to fight off bacteria and viruses. Inflammation is crucial to our survival, but sometimes inflammation can be bad for us. Long term inflammation that goes unchecked can cause heart attack and stroke. At the moment no treatment exists to manage such inflammation.