Clinical Trial 49079

Garden Grove, CA 92844


This research study is being done to test a potential treatment for hyperoxaluria. Hyperoxaluria results from having too much of a naturally occurring substance, called oxalate, being passed in the urine. Oxalate is normally found at a certain level in the body and also in many foods. The Sponsor of this study, has created a genetically modified study drug, NOV-001, with the goal of lowering oxalate levels in the urine. This is a research study to test this investigational drug.


Key Inclusion criteria

  1. Male/Female >18 and <55 years of age
  2. BMI <38 kg/m2
  3. Healthy: No clinically relevant abnormalities

Key Exclusion criteria (Cannot participate if you have the following):

  1. Current or Hx of drug abuse
  2. History of alcohol consumption – male: >14 drinks/week; female >21 drinks/week
  3. eGFR of over 80
  4. Renal disease
  5. Chronic diarrhea or constipation
  6. Bleeding disorder

Qualified Participants May Receive:

  • $160 per visit on average
  • Total: up to $3,400​​​​​​

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.