Plaque Psoriasis - San Diego CA

Summary:

Plaque Psoriasis is a chronic skin issue that over 7.5 million Americans face.
If you suffer from moderate to severe plaque psoriasis and have tried other antipsoriasis
treatments without success, consider enrolling in a research study at Skin Surgery Medical Group. Qualified participants ages 18-75 with diagnosed moderate to severe plaque
psoriasis would receive study-related care of a board-certified dermatologist and
compensated up to $800

Inclusion Criteria:

1. Are between the ages of 18 and 75 years, inclusive, at time of informed consent.
2. Capable of giving informed consent and complying with study procedures.
3. Willing and able to adhere to study restrictions.
4. Laboratory and medical history parameters within the protocol defined ranges.
5. Body mass index (BMI) of 18.0 to 35.0 kg/m2inclusive.
6. Have had a diagnosis of moderate-to-severe PP for at least 6 months prior to Baseline.

7. Participants with moderate-to-severe PP covering ≥10% body surface area (BSA), with a Psoriasis Area and Severity Index (PASI) ≥12 and a static Physician's Global Assessment (PGA) score ≥3 at Baseline.

Exclusion Criteria:

1. Pregnant or nursing women.
2. History of chronic alcohol or drug abuse within 6 months prior to Screening as determined by the Investigator based on medical history and patient interview
3. Current or recent history of severe, progressive, or uncontrolled renal, hepatic, hematologic, gastrointestinal, metabolic, endocrine, pulmonary, cardiovascular, neurologic, or psychiatric disease.
4. Current and/or recent history (<30 days prior to Screening and/or <45 days prior to randomization) of a clinically significant viral, bacterial, fungal, parasitic, or mycobacterial infection.
5. Any history of malignancies, except for non-recurrent basal cell skin cancer, squamous cell skin cancer, and cervical cancer in situ that are considered to be cured.
6. Tests positive for hepatitis B, hepatitis C, or human immunodeficiency virus (HIV). Hepatitis B test result positive definition: 1) hepatitis B surface antigen (HBsAg) positive, or 2) Hepatitis B core antibody positive and hepatitis B virus deoxyribonucleic acid positive or beyond the upper limit of normal (ULN) value; positive hepatitis C virus result is defined as having a positive hepatitis C antibody test with a positive confirmatory hepatitis C polymerase chain reaction test.
7. Recent exposure to active tuberculosis (TB). Current evidence of active TB or current evidence of latent TB. Participants with positive TB test (e.g., QuantiFERON) that have been treated for latent TB.
8. Previous or current autoimmune diseases (e.g., RA, systemic lupus erythematosus, IBD, scleroderma, inflammatory myopathy, mixed connective tissue disease overlap syndrome, etc.). Note, psoriatic arthritis patients are allowed.
9. Other types of psoriasis (such as erythrodermic psoriasis, pustular psoriasis, guttate psoriasis, drug-induced psoriasis)

More criteria may apply reachout to clinic to find out more details.

Qualified Participants May Receive:

Those who qualify have a 75% receiving the study drug and 25% a placebo. The study drug is an oral treatment. 

Participants will receive $100 for each completed study visit.