Summary:
This study is looking for people between the ages of 18 and 65 who are of African or Hispanic ancestry (which may include but is not limited to the following: Black, Caribbean, African American, sub-Saharan African, or Latinx [defined as a person of Caribbean, South or Central American, or similar descent]) and have a history of increased protein levels in their urine with no evidence of another underlying kidney disease.
If you have been diagnosed with kidney disease, have symptoms of kidney disease, or have a family history of kidney problems, this clinical research study may be an option for you. Those who qualify will receive a no cost investigational genetic test to see if they have a genetic variation of the apolipoprotein L1 (APOL1) gene. This gene variant is associated to high risk of losing kidney function. This study consists of one onsite visit. At this visit, the study doctor and their team will take samples of blood and saliva from study volunteers to see if they were born with a variation in their APOL1 gene that is related to CKD.
Qualified Participants Must:
• Between 18-65 years of age
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Diagnosed with chronic kidney disease or focal segmental glomerulosclerosis (FSGS)
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Increased level of protein in urine
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No history or diabetes
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Of African or Hispanic ancestry
Qualified Participants May Receive:
Those who qualify will receive APOL1 investigational genetic testing at no cost, genetic counseling is available and may be compensated for study-related time and reimbursed for travel. The results of this test may qualify participants for a future clinical research study exploring treatment options for people with CKD.