Expired Study
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Clinical Trial 921

Durham, NC 27710


Study Summary:

Do You Have Heart Disease? Are you interested in Exercise? If you have a history of heart disease (heart attack, revascularization procedure or cardiac catheterization) and have symptoms of depression such as feelings of sadness, loss of interest, fatigue, sleep disturbance, or feelings of worthlessness, you may qualify for a research study evaluating the effects of exercise or medication on symptoms of depression and important cardiovascular risk markers. Eligible participants will receive a medical screening and assessment of cardiovascular function along with a 4-month treatment program of exercise or medication (sertraline or placebo). Assessments and treatment will be provided at no cost, and participants will be compensated for completing the study. free web page hit counter


Qualified Participants Must:

• Have experienced a heart attack, had a coronary angioplasty, stenting, or bypass surgery, or had an abnormal cardiac catheterization
• Be experiencing any symptoms of depression
• Be 35 years or older
• NOT currently taking antidepressant medication, exercising regularly, or in psychotherapy


Qualified Participants May Receive:

Medical and psychological assessments at no cost; Exercise or medication at no cost; compensation for time and travel


Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.