Summary:
You are invited to take part in this study as an adult with Parkinson’s Disease or as a Healthy Volunteer. This is an early phase clinical imaging study to evaluate the safety of an investigational drug called [18F]MK-0947, which is designed to help doctors see changes in the brain related to Parkinson's disease (PD) with a PET (Positron Emission Tomography) scan to show areas of the brain where a protein called α-synuclein builds up. This buildup is linked to PD and other brain disorders. The study will also look at how the drug moves through the body and how much radiation it gives off after a small dose. Researchers hope this information will help develop better tools for diagnosing PD and tracking how it changes over time.
Inclusion Criteria:
- PD & Healthy Older participants: Age 40-80 years
- Also, Healthy participants: Age 18-50 years
- Adequate circulation and normal clotting for blood access.
- Must be able to undergo MRI of the brain.
Other conditions for Inclusion/Exclusion in the study will be discussed with the applicant by our medical staff.
Qualified Participants May Receive:
You are eligible for a stipend to help cover the cost of travel
and expenses, such as parking, babysitting, time off from work, meals, etc. Parkinson’s
participants and Older Healthy volunteers will receive up to a total of $1,500
for completion of Part 1A the study. For Part 1B, Parkinson’s participants will
receive up to a total of $1,000 for completion. Healthy volunteers for Part II
of the study will receive up to a total of $1,200 for completion of the study.